

The data presented is the change in the 'worst' phantom limb pain at 6 and 12 months from the baseline measurement. It is estimated that phantom limb pain (PLP) affects anywhere from 40 to 80 of amputees. They can present as kinetic, kinesthetic, or exteroceptive perceptions.
#Phantom pain management clinical trials boston trial
Implications The article reports for the first time a randomized controlled trial of mirror therapy in a homogenous sample of persons with traumatic amputations. The 'worst' phantom limb pain experienced over the previous 3 days evaluated with the 0-10 Numeric Rating Scale with 0no pain and 10worst imaginable pain. Purpose of review: Phantom sensations are incompletely understood phenomena which take place following an amputation or deafferentation of a limb. Conclusions The study documents that a 4-week treatment period with mirror and/or tactile therapy significantly reduces PLP and stump pain after trans-tibial amputations. After treatment, the reduction of pain remained unchanged for an observation period of 3 months. The difference between the three treatment arms were however slight, and hardly of clinical relevance. .clinical trials, and their efficacies are instead based on positive treatment response for other neuropathic pain. Combined mirror-tactile treatment had a significantly better effect on PLP and stump pain than mirror or tactile therapy alone. Results All three interventions were associated with more that 50% reduction in visual analogue scale (VAS)-rated PLP and stump pain. Endpoint estimates of phantom limb pain (PLP), stump pain, and physical function were registered 3 months after the treatment. Power analysis: a point was given if sample size was determined through the use of a power analysis. The intervention consisted of 5 min of treatment every morning and evening for 4 weeks. Pain intensity: to ensure that the trial evaluated clinically significant pain, a point was given if mean visual analog pain scores were greater than 30 mm or greater than 3 of 10 on a numeric rating scale. Non-responders from the mono-therapy interventions were crossed over to the alternative intervention.

A study sample of 45 landmine victims with trans-tibial amputations was allocated to three treatment arms mirror therapy, tactile therapy, and combined mirror-and-tactile therapy. Methods The study was conducted with an open, randomized, semi-crossover case-control design in rural Cambodia. Background and aims The aim of the study was to examine the effect of mirror and tactile therapy on phantom and stump pain in patients with traumatic amputations, with particular reference to amputees in low-income communities.
